Light effects on the activity of several genes have recently been exploited in studies of plant gene expression. We discuss here some examples involving nuclear genes of higher plants, with emphasis on responses mediated by the phytochrome system. Recent work has revealed considerable diversity in the responses of different genes, indicating that several different regulatory programs are probably involved. A start has been made in studies of nuclear events associated with the changes in expression. Transcriptional regulation almost certainly occurs, although (...) many details remain to be studied and effects on mRNA processing and turnover have not been ruled out. Recent in vitro mutagenesis and gene transfer experiments with the gene for the small subunit of RuBP carboxylase indicate that sequences involved in regulating the level of expression in the light are located 5′ to the gene within about 1 kb of the start of transcription. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in (...) the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy—the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic process that transcends the substrate in which it occurs, evolution’s creativity is not limited to nature. Indeed, many researchers in the field of digital evolution have observed their evolving algorithms and organisms subverting their intentions, exposing unrecognized bugs in their code, producing unexpected adaptations, or exhibiting outcomes uncannily convergent with ones in nature. Such stories routinely reveal (...) creativity by evolution in these digital worlds, but they rarely fit into the standard scientific narrative. Instead they are often treated as mere obstacles to be overcome, rather than results that warrant study in their own right. The stories themselves are traded among researchers through oral tradition, but that mode of information transmission is inefficient and prone to error and outright loss. Moreover, the fact that these stories tend to be shared only among practitioners means that many natural scientists do not realize how interesting and lifelike digital organisms are and how natural their evolution can be. To our knowledge, no collection of such anecdotes has been published before. This paper is the crowd-sourced product of researchers in the fields of artificial life and evolutionary computation who have provided first-hand accounts of such cases. It thus serves as a written, fact-checked collection of scientifically important and even entertaining stories. In doing so we also present here substantial evidence that the existence and importance of evolutionary surprises extends beyond the natural world, and may indeed be a universal property of all complex evolving systems. (shrink)

In this reply to James H. Fetzer’s “Minds and Machines: Limits to Simulations of Thought and Action”, I argue that computationalism should not be the view that (human) cognition is computation, but that it should be the view that cognition (simpliciter) is computable. It follows that computationalism can be true even if (human) cognition is not the result of computations in the brain. I also argue that, if semiotic systems are systems that interpret signs, then both humans and computers are (...) semiotic systems. Finally, I suggest that minds can be considered as virtual machines implemented in certain semiotic systems, primarily the brain, but also AI computers. In doing so, I take issue with Fetzer’s arguments to the contrary. (shrink)

The Doctrine of Double Effect (DDE) is an influential non-consequentialist principle positing a role for intention in affecting the moral permissibility of some actions. In particular, the DDE focuses on the intend/foresee distinction, the core claim being that it is sometimes permissible to bring about as a foreseen but unintended side-effect of one’s action some harm it would have been impermissible to aim at as a means or as an end, all else being equal. This article explores the meaning and (...) application of the DDE along with current debates over the nature of the intend/foresee distinction and its moral significance. How is the line between intended effects and merely foreseen but unintended side-effects to be drawn, and how are problem cases best handled? What is an appropriate methodology for debating the tenability of the DDE? How might the DDE interact with other non-consequentialist principles, and how might it be modified to capture other related factors (resulting perhaps in a Doctrine of Triple Effect) or to avoid certain problem cases? Does the DDE make permissibility turn on the actual intentions of particular agents, as critics such as Thomson and Scanlon assume, or is the role of intention more abstract? (shrink)

Philosophy has been characterized (e.g., by Benson Mates) as a field whose problems are unsolvable. This has often been taken to mean that there can be no progress in philosophy as there is in mathematics or science. The nature of problems and solutions is considered, and it is argued that solutions are always parts of theories, hence that acceptance of a solution requires commitment to a theory (as suggested by William Perry's scheme of cognitive development). Progress can be had (...) in philosophy in the same way as in mathematics and science by knowing what commitments are needed for solutions. Similar views of Rescher and Castañeda are discussed. (shrink)

We develop and apply a multi-dimensional account of explanatory depth towards a comparative analysis of inflationary and bouncing paradigms in primordial cosmology. Our analysis builds on earlier work due to Azhar and Loeb (2021) that establishes initial conditions fine-tuning as a dimension of explanatory depth relevant to debates in contemporary cosmology. We propose dynamical fine-tuning and autonomy as two further dimensions of depth in the context of problems with instability and trans-Planckian modes that afflict bouncing and inflationary approaches respectively. In (...) the context of the latter issue, we argue that the recently formulated trans-Planckian censorship conjecture leads to a trade-off for inflationary models between dynamical fine-tuning and autonomy. We conclude with the suggestion that explanatory preference with regard to the different dimensions of depth is best understood in terms of differing attitudes towards heuristics for future model building. (shrink)

A standard line in the contemporary philosophical literature has it that physical theories are equivalent only when they agree on their empirical content, where this empirical content is often understood as being encoded in the equations of motion of those theories. In this article, we question whether it is indeed the case that the empirical content of a theory is exhausted by its equations of motion, showing that (for example) considerations of boundary conditions play a key role in the empirical (...) equivalence (or otherwise) of theories. Having argued for this, we show that philosophical claims made by Weatherall (2016) that electromagnetism in the Faraday tensor formalism is equivalent to electromagnetism in the vector potential formalism, and by Knox (2011) that general relativity is equivalent to teleparallel gravity, can both be called into question. We then show that properly considering the role of boundary conditions in theory structure can potentially restore these claims of equivalence and close with some remarks on the pragmatics of adjudications on theory identity. (shrink)

Canonically, ‘classic’ tests of general relativity (GR) include perihelion precession, the bending of light around stars, and gravitational redshift; ‘modern’ tests have to do with, _inter alia_, relativistic time delay, equivalence principle tests, gravitational lensing, strong field gravity, and gravitational waves. The orthodoxy is that both classic and modern tests of GR afford experimental confirmation of that theory _in particular_. In this article, we question this orthodoxy, by showing there are classes of both relativistic theories (with spatiotemporal geometrical properties different (...) from those of GR) and non-relativistic theories (in which the lightcones of a relativistic spacetime are ‘widened’) which would also pass such tests. Thus, (a) issues of underdetermination in the context of GR loom much larger than one might have thought, and (b) given this, one has to think more carefully about what exactly such tests in fact _are_ testing. (shrink)

Recent business headlines, particularly those related to the collapsed energy-trading giant, Enron and its auditor, Arthur Andersen raise concerns about accountants' ethical reasoning. We propose, and provide evidence from 90 new auditors from Big-Five accounting firms, that a selection-socialization effect exists in the accounting profession that results in hiring accountants with disproportionately higher levels of the Sensing/thinking (ST) cognitive style. This finding is important and relevant because we also find that the ST cognitive style is associated with relatively low levels (...) of ethical reasoning, regardless of gender. This finding implies a need for emphasis on the ethical training of accountants. The results also suggest that accounting firms should consider recruiting accountants with cognitive styles associated with relatively higher levels of ethical reasoning. (shrink)

This paper argues that we ought to conceive of the Dark Energy problem—the question of how to account for observational data, naturally interpreted as accelerated expansion of the universe—as a crisis of underdetermined pursuit-worthiness. Not only are the various approaches to the Dark Energy problem evidentially underdetermined; at present, no compelling reasons single out any of them as more likely to be true than the other. More vexingly for working scientists, none of the approaches stands out as uncontroversially preferable over (...) its rivals in terms of its rationally warranted promise, i.e. the reasons to further work on, explore, and develop it. We demonstrate this claim by applying a Peircean economic model of pursuit-worthiness in terms of a cognitive cost/benefit estimate—with the instantiation of theory virtues as key indicators of cognitive gains—to the four main Dark Energy proposals (the cosmological constant approach, modified gravity, quintessence, and inhomogeneous cosmologies). According to our analysis, these approaches do not admit of an unambiguous, or uncontroversial, ranking with respect to which ansatz deserves distinguished attention and research efforts. The overall methodological counsel that our analysis underwrites recommends a pragmatic double research strategy forward: to encourage and foster theory pluralism and the search for tests—with the goal of enhancing the testability of the \(\Lambda \) CDM model and “testing it to destruction". (shrink)

The doctrine of the spiritual senses has played a significant role in the history of Roman Catholic and Eastern Orthodox spirituality. What has been largely unremarked is that the doctrine also played a significant role in classical Protestant thought, and that analogous concepts can be found in Indian theism. In spite of the doctrine’s significance, however, the only analytic philosopher to consider it has been Nelson Pike. I will argue that his treatment is inadequate, show how the development of the (...) doctrine in Puritan thought and spirituality fills a serious lacuna in Pike’s treatment, and conclude with some suggestions as to where the discussion should go next. (shrink)

An outline is given of the proof that the consistency of a κ⁺-Mahlo cardinal implies that of the statement that I[ω₂] does not include any stationary subsets of Cof(ω₁). An additional discussion of the techniques of this proof includes their use to obtain a model with no ω₂-Aronszajn tree and to add an ω₂-Souslin tree with finite conditions.

His authority is always grounded in the very authority he deposes, with the result that his voice is little more than a theatrical performance that unwittingly re-enacts the rhetorical maneuvers of deposed father figures.

Scholars have remained undecided how much the British Idealists owe to Hegel, how much to Kant, and how much they may be credited with minting a new intellectual coinage of their own. By way of a detailed examination of T. H. Green’s metaphysics of free will and how it stands to both its Kantian and its Hegelian predecessors, this paper attempts to make some headway on that longstanding question of pedigree. It is argued that by translating previously naturalistic considerations about (...) free will into Kantian or atemporalist terms, Green makes some useful and important advances. But he still remains subject to the tension between libertarian and autonomous approaches to the issue. It might be wondered whether any theory could ever reconcile these two approaches, but it is argued that by filtering his Kantianism through a more Hegelian lens, Green manages somewhat to reduce the friction between these two perspectives and to get closer to his ideal of a unified theory of human free will. (shrink)

The question I want to pursue here is one that I have lifted from Harry Frankfurt’s recent surprising best-selling book, On Bullshit, in which he asks why there is so much bullshit today in Western cultures like the U. S. The scope of Frankfurt’s charge was deliberately broad. It’s not just that people bullshit about how much money they make or how important their jobs are, but that public discourse about just any topic of consequence in American culture is filled (...) with, one is even tempted to say consists of, such unseemly speech. Such is the case, I want to claim here, about public discourse about sport in the print and visual media, in everyday life, and even, as I will shortly comment upon, in so-called academic and civic forums. So I don’t think it is a stretch at all, nor do I believe Frankfurtwould regard it as such, to include sport among the topics about which bullshit abounds. He might, however, quibble with my claim that the preponderance of bullshit in and outside of sport circles has mainly to do with the incursion of the market into most of the social practices that people hold dear in our culture. This despite the fact that Frankfurt does recognize that one primary reason why bullshit dominates so much of our contemporary discourse is that people are frequently called upon to speak about things that exceed their grasp, their knowledge of the subject. What he seems not to appreciate in this regard, however, is that one especially important reason why people’s grasp of what they say and do leaves much to be desired is because more often than not it is market actors that are doing all the talking here, whether the topic be sports, or politics, or even science. And the reason they are doing all the talking is the same reason they are mostly responsible for what actually goes on in these disparate spheres, namely, they hold and control the purse strings. So I’m persuaded, more than Frankfurt apparently is, that it is because the money-changers dominate sports, as I have insinuated they dominate most everything else, that what gets said in and about sports is mostly bullshit. Convincing you that I’m right about this will be my aim today, and that’s no bullshit, I think. (shrink)

In a series of important and influential books, Wilfred Cantwell Smith has convincingly argued that religious traditions are misunderstood if one does not grasp the faith which they express, that these traditions are not static but fluid, and that as a result of greater knowledge and increased contact between members of different traditions, we have entered a period in which it is no longer possible for the traditions to develop in relative isolation. This paper is devoted to an important aspect (...) of Smith's thought – his distinction between faith and propositional belief. (shrink)

In this comment I discuss the role of an ethics case consultant in an institutional setting, in contrast to situations when an ethics consultant serves an individual client. In the former situation, I believe the case consultant should articulate ethical issues, options, and arguments, but not recommend a particular course of conduct. In the latter situation, the role of the ethics consultant can be defined and determined in negotiations with the client.

John H. Evans’s views on the multiple roles of healthcare ethics consultants are based on his claim that bioethics is a “distinct profession” that has a “system of abstract knowledge.” This response to Professor Evans disputes both of his claims. It is argued that clinical ethicists are consultants but not professionals. Their roles as consultants require more than one abstract form of knowledge (principlism). Instead, clinical ethicists rely upon a variety of ethical perspectives and other skills to help resolve conflicts (...) and facilitate healthcare decisions and policy making, whether it is in clinical, research, policy, or organizational contexts. The credibility and effectiveness of clinical ethicists depend upon their knowledge of ethics, their practical experience, and personal abilities, not one form of abstract knowledge. (shrink)

The increasing role played by medical ethicists in the clinical setting both as teachers and consultants has brought with it a demand for new methodologies that speak more precisely to the multiple problems encountered in actual attempts at case resolution. Some of these moves have to do with a revival of the truly classic case study approach to ethics, casuistry. This approach is anchored in the revelatory text of Jonsen and Toulmin, TheAbuseofCasuistry. A fine example of this methodology is an (...) article in TheJournalofClinicalEthics, Conjoined to this approach is a renewed interest in virtue ethics. The groundwork for this was laid by MacIntyre's masterful history of its demise in AfterVirtue. A clear and concise application of this ancient but always new approach is given in Pellegrino and Thomasma's book TheVirtuesinMedicalPractice. This way of doing ethics is particularly congenial to the practice of healthcare ethics in that it understands that virtue is just a rather fancy name for a good habit or skill. Since the practice of clinical medicine is quintessentially the learning and application of a range of often highly complex patterns of professional abilities and skills, a virtue ethics approach will allow for the concomitant development of a whole set of ethical skills. But both casuistry and virtue ethics may well be seen to be operative in a larger context now known as narrative ethics. (shrink)

Persons who commit crimes involving sexual abuse of children exploit their victims in several ways. Sex offenders use their power and authority over vulnerable children to whom they have easy access. Teachers, coaches, clergy, family members and childcare workers have been exposed as sex offenders. The Pennsylvania State University football coach, Jerry Sandusky, is now in prison for his many crimes. The widespread cover up of sexual abuse by Catholic priests in the USA and other countries is a horrendous scandal. (...) It is not surprising that law enforcement, mental health professionals, victims and their families are outraged. It is no surprise that radical interventions such as chemical or surgical castration are a response to the public pressure to protect children from molestation.I agree with Professor John McMillan's thoughtful discussion and nuanced analysis of surgical castration.1i He concludes that surgical castration of sex offenders is ethically permissible if these conditions are met: Castration should be requested by the sex offender. Informed consent from a competent sex offender is required. Consent to castration must not be coerced via threats or inducements.He also says that “castration might be useful for the reconfiguring of a life that has gone badly awry.”To supplement his discussion I will describe a state law in Texas2 that permits voluntary surgical castration for repeat child molesters while they are incarcerated as …. (shrink)

This essay is a rudimentary effort at the functional specialization of dialectic. Following Lonergan’s maxim in Insight to develop positions and to reverse counterpositions, it takes a relatively simple puzzle about eisegesis and criticises some basic confusions about what goes “into” the reading of texts. In the process two counterpositions on the meaning of “text” are criticised and an alternative to both defended.

A glance at the daily newspaper reveals a myriad of moral imperfections in sport. Stories on drug use, violence, scandals, and unethical practices are nearly as common as recaps of the previous day's game. "Ethics in Sport" examines these and other key issues. It is the finest and most comprehensive literature to date on the ethical issues confronting sport in contemporary society. The book includes - an examination of good sportsmanship, fair play, and cheating and their true places in today's (...) sport environment; -an ethical exploration of the most dominant, moral controversy in sport today - performance-enhancing drugs; -a review of gender equity and identity in modern-day sport, including a look into the strides that women have made and the male "paternalism" of sport that may hinder future progress;-an overview of animal rights in sport and the moral and ethical issues of exploiting, maiming, and even killing animals in the name of sport; -a look into sport's influence on society;-an assessment of violence in sport and its threat to the moral social fiber; and -an evaluation of whether sport still teaches values that are vital and beneficial. Ethics in Sport, Third Edition, offers 32 essays by well-known authors. These essays explore the roots of the ethical and moral dilemmas so prevalent in sport culture today. Nearly half the essays are new to this edition. (shrink)

This article recognises that any attempt to theorise the first wave globally must specify the use of the term ‘global’, so as not to elide the specificity of local differences, and must critically account for how feminist struggles among postcolonial, indigenous women are intertwined with a resistance to a history of colonialism and racial domination. While more than a demand for equal access to the symbolic order on the basis of gender alone, Western feminists must study carefully the cultural and (...) gender implications of work by indigenous women in postcolonial contexts which do not easily fit into familiar theoretical paradigms that mimic the development of Western feminism, given the heterosexist biases of Western feminism historically. To what extent does the very form of historicisation of feminist struggles in the West repeat the colonising gesture when attempting to historicise the struggles of women in postcolonial contexts where the three waves of feminism as an organising framework, however loosely constructed, are transplanted to locations where they did not emerge historically? Through an examination of feminist work coming out of southern Africa, the article argues how attention to affective and erotic bonds between women in Lesotho provides a critical response to the heterosexist biases of African cultural nationalism, as well as to the colonising tendencies of feminist and queer enquiry in the West that do not account for the primacy of the performativity of sexual expression rather than its discursive naming as a precise sexual identity. The article concludes by asking for a reconceptualisation of the temporality of feminism not limited to its periodisation in the West, but informed by the specificities of feminist struggles locally and globally, including erotic autonomy as a viable praxis of decolonisation and a heightened self-reflexivity about the imperialist gestures guiding the production of (feminist) history and scholarship. (shrink)